ReBeautTM – Rebooting the Genetic Program to Restore Youthful Beauty
Ponce Therapeutics is developing a state-of-the-art biotechnology platform to restore the youthful balance of aged or “senescent” and young cells in the skin, targeting the senescent cells for elimination. This provides a “reboot” of one’s genetic program to turn the clock on one’s skin back to its youthful exuberance.
Proprietary Platform
Targeting Senescent Cells for Elimination
Elimination of pro-inflammatory senescent cells has been shown to suppress cancer and rejuvenate tissues by restoring stem cell niches to their healthy state.

Clinical Pipeline
Development of our lead program, PT-001mn
Lead program, PT-001mn, to deliver p16-directed riCasp9 to keratinocytes in treating Bowen’s lesions using proprietary delivery technology.
Ponce Therapeutics Executes Worldwide Exclusive License to Speratum Biopharma’s Nano-in™ and No-Pass Mimic™ Nanoparticle Technologies in Anti-Aging and Other Products Initially for Skin
Ponce Therapeutic's ("Ponce") lead product, ReBeaut™, is a microneedle patch containing nanoparticles carrying its proprietary ApoptiCIDe™ cell elimination gene therapy technology targeting senescent keratinocytes and fibroblasts in the skin Speratum Biopharma ("Speratum")…
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